The “Imagerie des Sciences du Vivant de Grenoble” platform is dedicated to preclinical and clinical imaging research. It brings together over 120 permanent researchers, 77 PhD students and postdoctoral researchers, chemists, physicists, engineers, technologists, biologists, pharmacists and physicians. Its objective is to develop, in a harmonious and coherent way, the most relevant tools, equipment and methodologies for the in vivo exploration of physiopathological processes in animal and human models. The performance of these systems exceeds that of commercial systems. The equipment and associated expertise are available to the academic and industrial scientific community.
Key imaging expertise and know-how developed as part of FLI’s scientific activities
Methodological research focuses on (i) new optical equipment, X-ray imaging and nuclear detectors, (ii) new optical and nuclear imaging agents, (iii) intra-vital microscopy, (iv) neurophysiology, (v) MRI perfusion imaging, (vi) stereotactic radiotherapy guided by tomographic imaging. The combination of these scientific, technological and applied expertises will enable us to achieve consistency on a larger scale in integrated multimodal imaging for new in vivo molecular imaging solutions.
Preclinical and clinical platforms / scientific managers
The hub comprises 6 main imaging platforms:
- Multimodal interventional imaging ( intraoperative MRI, SPECT, MEG, confocal microendoscopy, fluorescence microscopy): Clinatec – Vincent Auboiroux, Vincent.AUBOIROUX@cea.fr
- Optical and opto-acoustic imaging : Optimal – Véronique Josserand & Jean-Luc Coll, veronique.josserand@univ-grenoble-alpes.fr, jean-luc.coll@univ-grenoble-alpes.fr.
- Nuclear imaging and US : GAIA – Alexis Broisat & Catherine Ghezzi, alexis.broisat@inserm.fr, catherine.ghezzi@univ-grenoble-alpes.fr
- Clinical and preclinical MRI, MRI-guided FUS platform, high-resolution preclinical X-ray CT scanner, X-ray CT-guided stereotactic irradiation platform: IRMaGe – Emmanuel Barbier, Tiphaine Jouanno & Hélène Elleaume, emmanuel.barbier@univ-grenoble-alpes.fr, tiphaine.jouanno@univ-grenoble-alpes.fr, helene.elleaume@inserm.fr
- MRI, Neurophysiology, EEG, TMS: iRMaGe – Aurelie Campagne, aurelie.campagne@univ-grenoble-alpes.fr
- IntraVital Microscopy – IVM : linear, non-linear and photoacoustic – Boudewijn van der Sanden, boudewijn.vandersanden@univ-grenoble-alpes.fr
Associated research laboratories
U1039, https://lrb.univ-grenoble-alpes.fr; U1209, https://iab.univ-grenoble-alpes.fr; https://www.imagerie-optimal.fr, U1216 (team 5), https://neurosciences.univ-grenoble-alpes.fr; https://irmage.univ-grenoble-alpes.fr; U1205, CLINATEC, https://www.clinatec.fr; UMR 5250, https://dcm.univ-grenoble-alpes.fr, TIMC UMR5525 (SyNaBi team), https://www.timc.fr/SyNaBi, INSERM UA7, https://strobe.univ-grenoble-alpes.fr