Post-doctoral Position – molecular imaging and theranostic agents for dysangiogenic diseases
Background and mission :
The successful candidate will develop expertise in radiopharmaceutical development and molecular imaging (PET/CT and SPECT/CT) in the frame of the THERAnanoSTIC ANR project, and more widely in preclinical models of cardiovascular and oncologic dysangiogenic diseases. As part of a collaborative multi-disciplinary team, the postdoctoral associate will lead the radio-theranostic research initiative and will be responsible for:
• Development of novel imaging and therapeutic agents
• Testing lead agents in pre-established and new in vitro and in vivo model systems
• Perform corroborative ex vivo assays (e.g. flow cytometry, immunohistochemistry, gammacounting, autoradiography) assessment
The candidate will have access to state-of-the art lab equipment, departmental and interdepartmental core facilities to ensure success of this research initiative in C2VN and CERIMED, on the Health Campus “La Timone” in Marseille, France. The postdoctoral associate will be encouraged and supported in all aspects of career development and is expected to publish in leading scientific journals, present in national and international conferences, and participate in independent and collaborative grant applications.
Applicants with experience in radiochemistry, biochemistry, preclinical imaging and ex vivo assays
are encouraged to apply. Previous expertise with radiochemistry is not required, however, the applicant must be enthusiastic about learning and mastering these skills.
Diplomas required :
Desired Qualifications and Technical Skills: • PhD in Pharmacology, Biomedical Sciences, or related field with an emphasis on preclinical imaging
Skills required:
• Experience with nuclear imaging (PET/CT, SPECT/CT), radiochemistry, autoradiography, gammacounting, • Experience with preclinical models of cardiovascular and/or oncologic diseases, including handling of research animals • Experience with quantitative analyses of chemical, cells, and tissue (ability to perform immunofluorescence analyses, activity assays, Western blots, flow cytometry, SDS-PAGE, and related biochemical assays.) • Knowledgeable in one or more of the following: bioconjugate chemistry, radiochemistry, and separation/analytical methods including mass spectrometry, HPLC
Compensation :
Salary range: 2 500 – 3 000€ /month
Structure :
The postdoctoral position is opened for 2 years at the Center for Cardiovascular and Nutrition research (C2VN, UMR AMU INSERM 1263 INRAE 1260) and the European Center for Research in Medical Imaging (CERIMED, UAR AMU CNRS 2012), parts of Aix-Marseille University. The post doctoral research associate will join a collaborative team of radiopharmacists, biologists and imaging scientists focused on the development of next generation radio-theranostics agents.
More about C2VN: https://c2vn.univ-amu.fr/
More about CERIMED: https://plateformes-aix-marseille.univ-amu.fr/cerimed.html