The Paris Centre hub is made up of 4 major research centers integrated into the University of Paris and Sorbonne University, all located in the vicinity of university hospitals (HEGP, Sainte-Anne, Cochin, Bichat-Beaujon, Pitié-Salpêtrière). This proximity facilitates the development of transfer research focused on patient care. This is underpinned by the teams’ multimodal imaging expertise (MRI, PET, SPECT, US, Optical, CT, MEG-EEG, EPR, Magnetic Resonance Elastography and Ultrasound) and integrates several levels, from fundamental research in cognitive neuroscience and biomedical imaging methodology to in vivo imaging of small animals, clinical research and diagnosis and therapeutic follow-up of patients.
Key imaging expertise and know-how developed as part of FLI’s scientific activities
Imaging biomarkers are at the heart of the Paris Centre node’s research, the aim being to develop effective tools for diagnosis and for assessing prognosis and response to treatment. The research teams focus primarily on pathologies such as cancer, inflammation, infection and neurodegenerative diseases, with a particular emphasis on the liver, brain, skeletal muscle and cardiovascular system. Biomarkers are developed using structural, functional, cellular and molecular imaging. Particular emphasis is placed on the development and validation of new contrast agents for molecular imaging (biochemical axis) and innovative methods for functional imaging.
Hub laboratories :
- CRI – UMRS 1149
- Laboratory for Vascular Translational Science, LVTS – UMRS 1148
- PARCC – UMRS 970,
- NMR laboratory at the Institute of Myology,
- Biomedical Imaging Laboratory
- CIREN, GHU Paris
- Chemical and Biological Technologies for Health Unit, UTCBS-UMR1022
- Ondes et images / Institut Langevin
Preclinical and clinical platforms / managers
Small animal imaging :
- University of Paris PIV small animal imaging platform, comprising 4 HeGP sites, Cochin, Cordeliers, Pharma Descartes, headed by Bertrand Tavitian
- FRIM platform at the University of Paris, directed by François Rouzet
Integrative, cognitive and clinical neuroscience:
- Center for Research and Education in Neuroscience CIREN of the University of Paris and GHU Paris, directed by Catherine Oppenheim
- CENIRICM Pitié-Salpétrière, directed by Stéphane Lehéricy
Neuromuscular diseases :
- NMR Laboratory of the Institute of Myology directed by Harmen Reyngoudt & Benjamin Marty
Biological imaging at the Institut Pasteur :
- UTechs laboratory platform headed by Spencer Shorte